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Journal Club: Post-treatment HIV-1 controllers with a long term virological remission after the interruption of early initiated antiretroviral therapy

April 4, 2013 by Natalie Taha, BHK, UBC MD 2013 Candidate

Article reviewed Sáez-Cirión, A., Bacchus, C., Hocqueloux, L., Avettand-Fenoel, V., Girault, I., Lecuroux, C., and Rouzioux, C. (2013). Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study. PLoS Pathogens, 9(3), e1003211. http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1003211 Purpose of study To investigate 14 HIV-1 infected patients who achieved durable viral…

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Journal Club: Acceptability and behavioural effects of antibiotic prophylaxis for syphilis prevention

February 20, 2013 by Cindy Huang, UBC Family Practice, PGY2

Article reviewed Farley TA, Cohen DA, Kahn RH et al. The acceptability and behavioural effects of antibiotic prophylaxis for syphilis prevention. Sex Transm Dis. 2003 Nov;30(11):844-9. Pubmed link to abstract: http://www.ncbi.nlm.nih.gov/pubmed/14603093 Purpose of the study Local epidemics of syphilis continue in North America despite continued efforts by public health agencies to control syphilis. The current…

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Journal Club: Predictors and persistence after therapy in men with nongonococcal urethritis

December 12, 2012 by Marisa Ponzo, UBC Dermatology, PGY2

Article reviewed Seña, AC, Lensing S, Rompalo A et al. Chlamydia trachomatis, Mycoplasma genitalium, and Trichomonas vaginalis infections in men with nongonococcal urethritis: Predictors and persistence after therapy. J Inf Dis. 2012; 206: 357-65. Purpose of study The three main sexually transmitted infections (STIs) associated with nongonococcal urethritis (NGU) in men are Chlamydia trachomatis (CT),…

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Journal Club: First cervical, now oropharyngeal – the link between HPV and carcinoma

November 15, 2012 by Jessica Wilford, UBC Dermatology PGY2

Article Reviewed Gillison ML, Broutian T, Pickard RK, et al. Prevalence of oral HPV infection in the united states, 2009-2010. JAMA. 2012;307(7):693-703. Purpose of the study The goal of this study was to estimate the prevalence of oropharyngeal squamous cell cancer (OSCC) in the US.  There are 500,000 cases of OSCC per year worldwide, and…

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Journal Club: HIV Pre-Exposure Prophylaxis: Explaining the discrepancy in findings between two African studies

October 18, 2012 by Mike Fazio, Medical Student, University of British Columbia

Articles Reviewed Partners PrEP Study: Baeten JM et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. New England Journal of Medicine. 2012 Aug 2;367(5):399-410. FEM PrEP Study: Van Damme L et al. Pre-exposure prophylaxis for HIV infection among African women. New England Journal of Medicine. 2012 Aug 2;367(5):411-22. Purpose of study Pre-exposure…

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